C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/16 (2006.01) A61K 31/195 (2006.01) A61K 31/215 (2006.01) A61K 38/07 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/16 (2006.01) C07K 5/103 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2259425
HIV-1 protease inhibitors, each containing as the active ingredient a P2 peptide which is a peptide translated from the gene information of HIV-1 virus. The inhibitors contain each as the active ingredient a synthetic peptide having the same amino acid sequence as that of the P2 peptide or compounds analogous to the P2 peptide. These HIV-1 protease inhibitors are based on methionine-containing compounds which are particularly exemplified by peptides having the amino acid sequence Ala-Glu-Ala-Met-Ser-Gln-Val-Thr-Asn- Thr-Ala-Thr-Ile-Met.
Inhibiteurs de la protéase du VIH-1, contenant chacun, comme principe actif, un peptide P2 qui est un peptide traduit de l'information génique du virus VIH-1. Lesdits inhibiteurs contiennent chacun, comme principe actif, un peptide synthétique ayant la même séquence d'acides aminés que celle du peptide P2 ou de composés analogues à ce dernier. Ces inhibiteurs de la protéase du VIH-1 sont à base de composés contenant de la méthionine qui sont particulièrement représentés par des peptides ayant la séquence d'acides aminés Ala-Glu-Ala-Met-Ser-Gln-Val-Thr-Asn-Thr-Ala-Thr-Ile-Met.
Marks & Clerk
Nissui Pharmaceutical Co. Ltd.
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