Hiv-1 reporter viruses and their use in assaying anti-viral...

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/70 (2006.01) C12N 15/86 (2006.01) C12N 15/867 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2412217

The present invention relates to HIV-1 proviral constructs, which produce replication competent HIV-1 reporter viruses. The invention also relates to the use of these HIV-1 reporter viruses in high throughput screening of anti- viral compounds.

L'invention concerne des constructions provirales de VIH-1 qui produisent des virus marqueurs de VIH-1 aptes à la réplication. Elle concerne également l'utilisation de ces virus en criblage à haut rendement de composés antiviraux.

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