Hiv envelope-cd4 complexes and hybrids

Details Hiv envelope-cd4 complexes and hybrids Hiv envelope-cd4 complexes and hybrids

A - Human Necessities

61

K

A61K 39/00 (2006.01) A61K 39/21 (2006.01) C07H 21/04 (2006.01) C07K 17/00 (2006.01) C12N 5/02 (2006.01)

Patent

CA 2482744

Env-CD4 complexes and hybrids are disclosed that expose cryptic epitopes that are important in virus neutralization. Methods of diagnosis, treatment and prevention using the polynucleotides and polypeptides are also provided.

La présente invention a trait à des complexes et des hybrides Env-CD4 qui exposent des épitopes cryptiques importants dans la neutralisation virale. L'invention a également trait à des procédés de diagnostic, de traitement et de prévention mettant en oeuvre les polynucléotides et les polypeptides.

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