Hiv fusion inhibitor peptides with improved biological...

Details Hiv fusion inhibitor peptides with improved biological... Hiv fusion inhibitor peptides with improved biological...

C - Chemistry, Metallurgy

07

K

C07K 14/16 (2006.01) A61K 38/16 (2006.01) C07K 1/02 (2006.01) C07K 1/04 (2006.01) C07K 7/08 (2006.01) C12N 15/49 (2006.01) C40B 40/10 (2006.01)

Patent

CA 2651793

Provided is an HIV fusion inhibitor peptide having an amino acid sequence of any one of SEQ ID NO:9. SEQ ID NO:10, SEQ ID NO:11, SEQ ID NO:12, SEQ ID NO:13, SEQ ID NO:14, or SEQ ID NO: 15; and provided is a pharmaceutical composition comprising a HIV fusion inhibitor peptide and one or more of a pharmaceutically acceptable carrier and macromolecular carrier, and uses and methods of treatment provided by these compositions.

L'invention concerne un peptide inhibiteur de la fusion du VIH ayant une séquence d'acide aminé parmi l'une des SEQ ID NO:9, SEQ ID NO:10, SEQ ID NO:11, SEQ ID NO:12, SEQ ID NO:13, SEQ ID NO:14, ou SEQ ID NO: 15; et elle concerne aussi une composition pharmaceutique qui comprend un peptide inhibiteur de fusion du VIH, et un ou plusieurs porteurs pharmaceutiquement acceptables et un porteur macromoléculaire, et des utilisations et des méthodes de traitement conférées par ces compositions.

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