C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/48 (2006.01) A61P 31/18 (2006.01) C07K 14/16 (2006.01) C12N 15/09 (2006.01) C12N 15/49 (2006.01) C12N 15/869 (2006.01)
Patent
CA 2461056
The invention provides a nucleotide sequence that encodes an HIV-1 gag protein or fragment thereof containing a gag epitope and a second HIV antigen or a fragment encoding an epitope of said second HIV antigen, operably linked to a heterologous promoter. Preferred polynucleotide sequences further encodes nef or a fragment thereof and RT or a fragment thereof.
L'invention concerne une séquence nucléotidique codant une protéine gag VIH-1 ou son fragment contenant un épitope gag et un second antigène VIH ou un fragment codant un épitope du second gène VIH, lié de manière opérationnelle à un promoteur hétérologue. De préférence, des séquences polynucléotidiques codent nef ou son fragment et RT ou son fragment.
Beaton Andrew
Ertl Peter Franz
Gough Gerald Wayne
Lear Andrew
Tite John Philip
Glaxo Group Limited
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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