Hiv inhibiting 2-( 4-cyanophenylamino) pyrimidine derivatives

Details Hiv inhibiting 2-( 4-cyanophenylamino) pyrimidine derivatives Hiv inhibiting 2-( 4-cyanophenylamino) pyrimidine derivatives

C - Chemistry, Metallurgy

07

D

C07D 239/50 (2006.01) A61K 31/505 (2006.01) A61P 31/18 (2006.01) C07D 239/48 (2006.01)

Patent

CA 2599228

HIV replication inhibitors of formula (I) pharmaceut ically acceptable addition salts or stereochemically isomeric forms thereof, wherein X is NR4, S, SO or SO2; the preparation of these compounds as well as pharmaceutical compositions comprising these compounds; the use of these compounds for the prevention or the treatment of HIV infection.

L'invention porte sur des inhibiteurs de réplication du VIH de formule (I) dans laquelle: X est NR4, S, SO ou SO2; sur leurs sels d'addition pharmacocompatibles, ou leurs isomères stéréochimiques; sur leur préparation, sur des préparations pharmaceutiques les contenant; et sur leur utilisation pour la prévention ou le traitement des infections par le VIH.

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