C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 241/20 (2006.01) A61K 31/4965 (2006.01) A61P 31/18 (2006.01)
Patent
CA 2437785
This invention concerns compounds of formula (I) (see formula I) a N-oxide, a pharmaceutically acceptable addition salt, or a stereochemically isomeric form thereof; their use as a medicine for inhibiting HIV replication, their processes for preparation and pharmaceutical compositions comprising them.
L'invention concerne des composés représentés par la formule (I), un N-oxyde, un sel d'addition acceptable d'un point de vue pharmaceutique, une amine quaternaire et une forme isomérique stéréochimique de celle-ci, R<1-4> et X étant tels que définis dans les revendications. L'invention concerne également leur utilisation en tant que médicament servant à inhiber la réplication du VIH, leurs procédés de préparation et des compositions pharmaceutiques les contenant.
Compernolle Frans Josef Cornelius
Daeyaert Frederik Frans Desire
de Jonge Marc Rene
Heeres Jan
Hoornaert Georges Joseph Cornelius
Gowling Lafleur Henderson Llp
Janssen Pharmaceutica N.v.
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