Hiv integrase inhibitors

Details Hiv integrase inhibitors Hiv integrase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61K 31/5377 (2006.01) A61K 31/542 (2006.01) A61K 31/551 (2006.01) A61K 31/553 (2006.01) A61P 31/00 (2006.01) C07D 487/14 (2006.01) C07D 493/20 (2006.01) C07D 498/04 (2006.01) C07D 513/04 (2006.01) C07D 513/14 (2006.01)

Patent

CA 2600832

Compounds of Formula I are inhibitors of FHV integrase and inhibitors of FHV replication (I), wherein m, n, X, Rl, R2, R3, R4, R5, R6 R7; R8 R9 and R10 are defined herein. The compounds are useful for the prophylaxis or treatment of infection by HTV and the prophylaxis, treatment , or delay in the onset of AIDS. The compounds are employed against HTV infection and ADDS as compounds per se or in the form of pharmaceutically acceptable salts. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.

Les composés de la formule I sont des inhibiteurs de l~intégrase du FHV ainsi que des inhibiteurs de la réplication (I) du FHV. Dans la formule I, les éléments m, n, X, Rl, R2, R3, R4, R5, R6 R7; R8 R9 et R10 ont la définition ci-jointe. Les composés se révèlent utiles lors de la prophylaxie ou du traitement de l~infection par HTV ainsi que lors de la prophylaxie, du traitement, ou du retardement de l~apparition du SIDA. Les composés sont utilisés afin de lutter contre les infections HTV et l~ADDS en tant que composés tels quels ou sous forme de sels pharmaceutiquement acceptables. Les composés et leurs sels peuvent être utilisés en tant qu~ingrédients dans des compositions pharmaceutiques, voire en association avec d~autres antiviraux, immunomodulateurs, antibiotiques ou vaccins.

Affiliated with

Also associated with

Rating

Hiv integrase inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Hiv integrase inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hiv integrase inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1675131