Hiv integrase inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 317/34 (2006.01) A61K 31/15 (2006.01) A61K 31/195 (2006.01) A61K 31/222 (2006.01) A61K 31/357 (2006.01) A61K 45/06 (2006.01) A61P 31/18 (2006.01) C07C 59/90 (2006.01) C07C 239/20 (2006.01) C07C 251/32 (2006.01) C07C 251/48 (2006.01) C07C 255/64 (2006.01) C07C 259/06 (2006.01) C07D 295/185 (2006.01)

Patent

CA 2469592

The present invention relates to the inhibition of HIV integrase, and to the treatment of AIDS or ARC by administering compounds of the following formula, or a tautomer of said compound, or a pharmaceutically acceptable salt, solvate or prodrug thereof: (formula I) wherein R1, R2 and B1 are as defined herein.

La présente invention a trait à l'inhibition de l'intégrase du VIH, et au traitement du SIDA ou du para-SIDA par l'administration de composés représentés par la formule (I), ou d'un tautomère desdits composés, ou d'un sel pharmaceutiquement acceptable, d'un solvant ou d'un promédicament desdits composés. R?1¿, R?2¿ et B?1¿ sont tels que définis dans le descriptif de l'invention.

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