Hiv integrase inhibitors

Details Hiv integrase inhibitors Hiv integrase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 321/00 (2006.01) A01N 43/02 (2006.01) A01N 43/16 (2006.01) A61K 31/335 (2006.01) A61K 31/35 (2006.01) A61K 31/495 (2006.01) A61K 45/06 (2006.01) C07D 311/80 (2006.01) C07D 311/92 (2006.01) C07D 405/04 (2006.01)

Patent

CA 2280518

Natural products such as certain chaetochromins are described. These compounds are useful in the inhibition of HIV integrase, the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.

La présente invention a trait à des produits naturels tels que certaines chaétochromines. Ces composés sont utiles dans l'inhibition de la VIH intégrase, la prévention ou le traitement de l'infection par VIH et le traitement du SIDA, soit en tant que tels, soit comme sels pharmaceutiquement acceptables, comme ingrédients de composition pharmaceutique, en association ou non avec d'autres antiviraux, immunomodulateurs, antibiotiques ou vaccins. L'invention concerne également des procédés pour le traitement du SIDA et des procédés pour la prévention ou le traitement de l'infection par le VIH.

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