Hiv pharmaccines

C - Chemistry – Metallurgy – 12 – N

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C12N 15/62 (2006.01) A61K 39/21 (2006.01) C07K 14/16 (2006.01) C12N 15/49 (2006.01)

Patent

CA 2539864

The invention relates to a recombinant polypeptide comprising amino acid sequence derived from at least one of an HIV gag gene product; an HIV pol gene product; or an HIV nef gene product, said sequence being mutated with respect to the natural sequence of said gene product, and said sequence maintaining each of the naturally occurring CD8+ T cell epitopes of said gene product as defined in p17 and p24 (gag), amino acids 1-440 of RT (pol) and nef shown in Example 8. Furthermore the invention relates to nucleic acids encoding same, and viral vectors encoding same, and to their use in medicine and in immunisation and vaccination.

L'invention concerne un polypeptide de recombinaison comprenant une séquence d'acides aminés dérivée d'au moins un produit du gène gag du VIH, un produit du gène pol du VIH; ou un produit du gène nef du VIH, ladite séquence ayant subi une mutation par rapport à la séquence naturelle dudit produit génique, et conservant chacun des épitopes des lymphocytes T CD8+ naturels dudit produit génique tels que définis dans p17 et p24 (gag), les acides aminés 1-440 de RT (pol) et nef, tel que le montre l'exemple 8. L'invention concerne, de plus, des acides nucléiques et des vecteurs viraux codant pour ledit polypeptide, ainsi que leur utilisation en médecine, et dans l'immunisation et la vaccination.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Hiv pharmaccines does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Hiv pharmaccines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hiv pharmaccines will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1628784

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.