Hiv protease inhibitor combination

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/495 (2006.01) A61K 31/425 (2006.01) A61K 31/426 (2006.01) A61K 31/427 (2006.01) A61K 31/435 (2006.01) A61K 31/44 (2006.01) A61K 31/47 (2006.01) A61K 31/496 (2006.01) A61P 31/18 (2006.01) C07D 217/26 (2006.01) C07D 277/22 (2006.01) C07D 401/06 (2006.01)

Patent

CA 2197207

The combination of the HIV protease inhibitor Compound J and any one or more of four other potent HIV protease inhibitors is useful in the inhibition of HIV protease, the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.

En combinant le composé J inhibiteur de la protéase du VIH et un ou plusieurs des 4 autres inhibiteurs forts de la protéase du VIH, on peut prévenir ou traiter l'infection à VIH et traiter le SIDA. Ces combinaisons peuvent s'utiliser sous la forme de composés ou de leurs sels pharmacocompatibles, ou sous la forme d'ingrédients entrant dans des préparation pharmaceutiques, et en association ou non avec d'autres antiviraux, immunomodulateurs, antibiotiques ou vaccins. Sont également décrites des méthodes de traitement et de prévention du SIDA et de l'infection à VIH.

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