Hiv protease inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 217/26 (2006.01) A61K 31/47 (2006.01)

Patent

CA 2284163

HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.

Ces inhibiteurs de protéases du VIH, que l'on peut obtenir par synthèse chimique, sont capables d'inhiber ou de bloquer l'activité biologique de la protéase du VIH, ce qui provoque l'arrêt de la réplication du virus du VIH. Ces composés, ainsi que les compositions contenant comme principes actifs ces composés et facultativement d'autres agents antiviraux, conviennent au traitement de patients ou d'hôtes infectés par le virus du VIH, qui est connu pour provoquer le SIDA.

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