Hiv protease inhibitors, compositions containing the same,...

Details Hiv protease inhibitors, compositions containing the same,... Hiv protease inhibitors, compositions containing the same,...

C - Chemistry, Metallurgy

07

D

C07D 277/06 (2006.01) A61K 31/426 (2006.01) A61K 31/427 (2006.01) A61P 31/18 (2006.01) C07D 207/09 (2006.01) C07D 207/16 (2006.01) C07D 211/60 (2006.01) C07D 213/38 (2006.01) C07D 217/26 (2006.01) C07D 231/12 (2006.01) C07D 265/06 (2006.01) C07D 277/60 (2006.01) C07D 295/13 (2006.01) C07D 307/52 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01) C07D 471/08 (2006.01)

Patent

CA 2450265

Compounds of Formula (I), where the formula variables are as defined herein, are disclosed that advantageously inhibit or block the biological activity of the HIV protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with the HIV virus. Intermediates and synthetic methods for preparing such compounds are also described.

L'invention concerne des composés représentés par la formule (I) qui inhibent ou bloquent avantageusement l'activité biologique de la protéase VIH, les variables de cette formule étant tels que définis dans le descriptif. Ces composés, ainsi que les compositions pharmaceutiques qui les renferment, sont utilisés pour traiter les patients ou les organismes hôtes infectés par le virus du VIH. L'invention concerne par ailleurs les intermédiaires et les méthodes synthétiques de préparation de ces composés.

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