C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 237/22 (2006.01) A61K 31/16 (2006.01) C07C 233/66 (2006.01) C07C 311/18 (2006.01) C07C 311/19 (2006.01) C07D 207/26 (2006.01) C07D 241/04 (2006.01) C07D 295/185 (2006.01) C07D 303/36 (2006.01) C07D 307/77 (2006.01) C07D 307/93 (2006.01) C07D 401/06 (2006.01) C07D 405/06 (2006.01)
Patent
CA 2252918
Peptide analogs containing norbornene are HIV protease inhibitors. These compounds are useful in the prevention or treatment of infection by HIV and in the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.
Des analogues de peptides contenant du norbornène sont des inhibiteurs de la protéase du VIH. Ces composés, utiles dans la prévention ou le traitement d'une infection par le VIH et dans le traitement du sida, se présentent sous forme de composés, de sels acceptables en pharmacologie ou d'ingrédients de compositions pharmaceutiques, séparément ou en combinaison avec d'autres antiviraux, immunomodulateurs, antibiotiques ou vaccins. Des méthodes permettant de traiter le sida et de prévenir ou de traiter une infection par le VIH sont également décrites.
Hungate Randall W.
Kim Byeong Moon
Vacca Joseph P.
Gowling Lafleur Henderson Llp
Merck & Co. Inc.
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