C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/46 (2006.01) A61K 31/505 (2006.01) A61P 31/18 (2006.01) C07D 239/48 (2006.01) C07D 251/16 (2006.01) C07D 251/50 (2006.01) C07D 401/12 (2006.01)
Patent
CA 2406562
This invention concerns HIV replication inhibitors of for-mula (I)the N-oxides, the pharmaceutically acceptable addition salts, the quaternary amines and the stereochemically isomeric forms thereof, pro-vided that when Q is halo then Z is N; or when Q is polyhaloC1-6alkyl then Y is hydrogen or C1-6alkyl; their use as a medicine, their processes for preparation and pharmaceutical compositions comprising them.
L'invention concerne des inhibiteurs de la réplication du VIH selon la formule (I), des N-oxydes, les sels d'addition pharmaceutiquement acceptables, les amines quaternaires et les formes stéréochimiquement isomériques de ces derniers. Lorsque Q représente halo, Z représente N ou lorsque Q représente polyhaloalkyleC1-6 alors Y représente hydrogène ou alkyle C1-6. L'invention traite de l'utilisation de ces composés comme médicaments, de leurs procédés de préparations et de compositions pharmaceutiques les contenant.
de Corte Bart Lieven Daniel
de Jonge Marc Rene
Heeres Jan
Janssen Paul Adriaan Jan
Kavash Robert W.
Gowling Lafleur Henderson Llp
Janssen Pharmaceutica N.v.
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