Hla-a2.1 binding peptides and their uses

Details Hla-a2.1 binding peptides and their uses Hla-a2.1 binding peptides and their uses

A - Human Necessities

61

K

A61K 39/00 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/02 (2006.01) C07K 14/18 (2006.01) C07K 14/74 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2157510

The present invention provides the means and methods for selecting immunogenic peptides and the immunogenic peptide compositions capable of specifically binding glycoprotains encoded by HLA-A2.1 allele and inducing T cell activation in T cells restricted by the A2.1 allele. The peptides are useful to elicit an immune response against a desired antigen.

L'invention se rapporte à des moyens et à des procédés pour sélectionner des peptides immunogènes et aux compositions de peptides immunogènes capables de se lier spécifiquement à des glycoprotéines codées par l'allèle HLA-A2.1 et d'induire une activation des lymphocytes T dans des lymphocytes T restreints par l'allèle A2.1. Ces peptides sont utiles pour déclencher une réponse immunitaire contre un antigène désiré.

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