Hla-a24-restricted cancer antigen peptides

Details Hla-a24-restricted cancer antigen peptides Hla-a24-restricted cancer antigen peptides

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/47 (2006.01) C07K 14/82 (2006.01) C07K 16/32 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12P 21/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2489227

It is intended to provide an HLA-A24-restricted peptide originating in WT1 which has an activity of inducing CTL in vivo; a polynucleotide encoding this peptide; a cancer vaccine using the above peptide or polypeptide in vivo or in vitro; etc. The above cancer vaccine is usable in treating a large number of patients suffering from cancer.

Cette invention concerne un peptide à restriction HLA-A24 généré dans WT1 et présentant une activité d'induction de CTL in vivo. Cette invention concerne également un polynucléotide codant ce peptide ainsi qu'un vaccin contre le cancer utilisant ce peptide ou polypeptide in vivo ou in vitro, etc. Ce vaccin contre le cancer peut être utilisé pour traiter un grand nombre de patients atteints du cancer.

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