Hla binding peptides and their uses

Details Hla binding peptides and their uses Hla binding peptides and their uses

C - Chemistry, Metallurgy

07

K

C07K 7/00 (2006.01) A61K 38/00 (2006.01) A61K 38/04 (2006.01) A61K 38/08 (2006.01) C07K 7/04 (2006.01) C07K 7/06 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2400215

The present invention provides the means and methods for selecting immunogenic peptides and the immunogenic peptide compositions capable of specifically binding glycoproteins encoded by HLA alleles and inducing T cell activation in T cells restricted by the allele. The peptides are useful to elicit an immune response against a desired antigen.

La présente invention concerne les moyens et les procédés qui permettent de sélectionner des peptides immunogènes et des compositions de peptides immunogènes qui sont capables de lier spécifiquement des glycoprotéines codées par des allèles HLA et d'induire une activation des cellules T dans des cellules T restreintes par l'allèle. Ces peptides sont utiles pour solliciter une réponse immunitaire contre un antigène désiré.

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