Hla-binding peptides and their uses

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/00 (2006.01) A61K 39/29 (2006.01) C07K 7/00 (2006.01) C07K 14/02 (2006.01) C07K 14/36 (2006.01) C07K 14/82 (2006.01)

Patent

CA 2323632

The present invention provides the means and methods for selecting immunogenic peptides and the immunogenic peptide compositions capable of specifically binding glycoproteins encoded by HLA allele and inducing T cell activation in T cells restricted by the allele. The peptides are useful to elicit an immune response against a desired antigen.

L'invention concerne les appareils et les procédés permettant de sélectionner des peptides immunogènes et des compositions de peptides immunogènes capables de lier spécifiquement des glycoprotéines codées par un allèle HLA et induisant l'activation des lymphocytes T dans les lymphocytes limités par l'allèle. Les peptides sont utilisés pour provoquer une réaction immunitaire contre un antigène souhaité.

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