Hla-dr-specific antibodies, compositions and methods

Details Hla-dr-specific antibodies, compositions and methods Hla-dr-specific antibodies, compositions and methods

C - Chemistry, Metallurgy

07

K

C07K 16/00 (2006.01) A61K 39/395 (2006.01)

Patent

CA 2550155

HLA-DR-specific monoclonal antibodies are provided that are capable of inducing apoptosis in HLA-DR-expressing tumor cells. Certain exemplary HLA-DR- specific antibodies exhibit reduced levels of immunosuppressive activity. Antibodies of the present invention will find use in diagnostic methods as well as in compositions and methods for the treatment of cancers associated with HLA-DR expressing tumor cells.

L'invention concerne des anticorps monoclonaux spécifiques de HLA-DR capables d'induire une apoptose dans des cellules tumorales exprimant HLA-DR. Certains anticorps spécifiques de HLA-DR exemplaires présentent des niveaux réduits de l'activité immunosuppresseur. Les anticorps de ladite invention trouvent leur utilisation dans des méthodes diagnostiques, ainsi que dans des compositions et des méthodes destinées au traitement de cancers liés aux cellules tumorales exprimant HLA-DR.

Affiliated with

Also associated with

Rating

Hla-dr-specific antibodies, compositions and methods does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Hla-dr-specific antibodies, compositions and methods, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hla-dr-specific antibodies, compositions and methods will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1924991