Hla-g proteins and pharmaceutical uses thereof

Details Hla-g proteins and pharmaceutical uses thereof Hla-g proteins and pharmaceutical uses thereof

A - Human Necessities

61

K

A61K 38/17 (2006.01) A61K 47/48 (2006.01) A61P 29/00 (2006.01) A61P 37/06 (2006.01) C07K 14/705 (2006.01) C12N 5/10 (2006.01) C12N 15/62 (2006.01) C12N 15/79 (2006.01)

Patent

CA 2742517

The present invention relates to novel proteins and pharmaceutical uses thereof. The invention more specifically relates to novel fusion proteins comprising a domain of an HLA-G antigen fused to an Fc domain of an immunoglobulin. The invention also relates to methods of producing such polypeptides, pharmaceutical compositions comprising the same, as well as their uses for treating various diseases including organ/tissue rejection.

Cette invention concerne de nouvelles protéines et leurs utilisations pharmaceutiques et, spécifiquement, concerne de nouvelles protéines de fusion comprenant un domaine dun antigène HLA-G fusionné à un domaine Fc dune immunoglobuline. Linvention concerne également des méthodes de production de polypeptides, des compositions renfermant lesdits polypeptides ainsi que leurs utilisations pour le traitement de diverses maladies, y compris le rejet dorganes/tissus.

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