Hm1.24 antigen expression potentiators

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/21 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) A61P 19/00 (2006.01) A61P 35/00 (2006.01) C07K 16/30 (2006.01) G01N 33/15 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2382587

Potentiators for the expression of HM1.24 antigen in myeloma cells which contain as the active ingredient interferon .alpha., interferon .gamma. or IRF- 2 protein. It is estimated that interferons .alpha. and .gamma. potentiate the expression of HM1.24 antigen through the activation of the promoter of a gene encoding HM1.24 antigen.

La présente invention concerne des potentialisateurs d'expression de l'antigène HM1.24 dans les cellules de myélome, qui contiennent l'interféron .alpha., l'interféron .gamma. ou la protéine IFR-2 comme composants actifs. On estime que l'interféron .alpha. et l'interféron .gamma. potentialisent l'expression de l'antigène HM1.24 via l'activation du promoteur d'un gène codant pour cet antigène HM1.24.

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