Hmb compositions and uses thereof

Details Hmb compositions and uses thereof Hmb compositions and uses thereof

A - Human Necessities

61

K

A61K 31/19 (2006.01) A61K 31/202 (2006.01) A61K 31/205 (2006.01) A61K 31/702 (2006.01) A61P 1/12 (2006.01) A61P 1/16 (2006.01) A61P 3/02 (2006.01) A61P 11/00 (2006.01) A61P 13/12 (2006.01) A61P 19/02 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2560042

The present invention relates to methods for the prevention and treatment of chronic inflammatory diseases, cancer, and involuntary weight loss. In the practice of the present invention patients are enterally administered HMB alone or alternatively in combination with eicosapentaenoic (20:5 w-3), FOS, carnitine and mixtures thereof. HMB may be added to food products comprising a source of amino-nitrogen enriched with large neutral amino acids such as leucine, isoleucine, valine, tyrosine, threonine and phenylalanine and subtantially lacking in free amino acids.

La présente invention porte sur des méthodes de prévention et de traitement de maladies inflammatoires chroniques, du cancer et de la perte de poids involontaire. Ces méthodes consistent à administrer aux patients le HMB par voie entérale, seuil ou alternativement, en combinaison avec (20:5 w-3) eicosapentaénoïque, FOS, carnitine et des mélanges de ceux-ci. HMB peut être ajouté à des denrées alimentaires comprenant une source d'amino azote enrichi en de grandes quantités d'acides aminés neutres tels que la leucine, l'isoleucine, la valine, la tyrosine, la thréonine et la phénylalanine et quasiment exemptes d'acides aminés libres.

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