Hmg-coa reductase inhibitors

C - Chemistry – Metallurgy – 07 – C

Patent

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167/244, 167/255

C07C 69/30 (2006.01) A61K 31/365 (2006.01) C07D 309/30 (2006.01)

Patent

CA 1286683

TITLE OF THE INVENTION NOVEL HMG-CoA REDUCTASE INHIBITORS ABSTRACT OF THE DISCLOSURE Novel 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors which are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I) or (II): Image (I) Image (II) and pharmaceutically acceptable salts thereof the compounds of the formula (II) in which R1 is hydrogen are disclosed.

570234

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