Hmg-coa reductase inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 207/34 (2006.01) A61K 31/40 (2006.01)

Patent

CA 2492162

The invention relates to particular hydroxyl and protected hydroxyl derivatives of compounds known to be useful as HMG CoA-reductase inhibitors. In particular, herein are provided hydroxyl and protected hydroxyl compounds of Formula I and their corresponding lactones.

Cette invention a trait à un hydroxy particulier ainsi qu'à des dérivés d'hydroxy protégé de composés connus pour leur utilité comme inhibiteurs de la HMG CoA-réductase. Elle porte, notamment, sur des composés d'hydroxy et d'hydroxy protégé, correspondant à la formule (I), et aux lactones correspondant.

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