A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01)
Patent
CA 2553679
The use of molecules that modulate the action of HMGB1 protein (or molecules having sequence homology) for the preparation of therapeutic agents for the treatment of diseases to related to endothelial and smooth muscle cells proliferation; said proliferation can be due to endothelium damage, caused by surgical operation and manipulation made on or through blood vessels, including coronary and/or carotid angioplasty, angiographic surgery, and surgery using catheters.
La présente invention a trait à l'utilisation de molécules de modulation de l'action de la protéine HMGB1 (ou des molécules présentant une homologie de séquence) pour la préparation d'agents thérapeutiques pour le traitement de maladies liées à la prolifération de cellules endothéliales et de muscles lisses ; ladite prolifération peut être due à la détérioration de l'endothélium, provoquée par une opération chirurgicale et la manipulation pratiquée sur ou à travers les vaisseaux sanguins, comprenant l'angioplastie coronaire et/ou de la carotide, la chirurgie angiographique, et la chirurgie au moyen de cathéters.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Bianchi Marco E.
Bio3 Research Srl
LandOfFree
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