Hnrnp a3 related peptides and use thereof for diagnosis of...

C - Chemistry – Metallurgy – 07 – K

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C07K 14/47 (2006.01) G01N 33/564 (2006.01)

Patent

CA 2748308

The invention relates to a peptide and retro or retro-inverso peptide thereof, with a length of <= 25 amino acid residues, characterized in that the peptide comprises at least one citrulline residue, and exhibits a sequence identity over the whole sequence of the peptide of >= 70% compared to human hnRNP A3 protein (SEQ ID No. 1) and uses thereof.

La présente invention concerne un peptide et l'un de ses rétro-peptides ou rétro-inverso-peptides, de longueur inférieure ou égale à 25 résidus acides aminés, caractérisés en ce que le peptide comprend au moins un résidu citrulline, et qu'il présente une identité de séquence sur toute la séquence du peptide supérieure ou égale à 70 % vis-à-vis de la protéine hnRNP A3 humaine (SEQ ID No. 1), ainsi que ses applications.

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