Hollow fiber bioreactor comprising a hydrogel flow restrictor

Details Hollow fiber bioreactor comprising a hydrogel flow restrictor Hollow fiber bioreactor comprising a hydrogel flow restrictor

C - Chemistry, Metallurgy

12

M

C12M 3/06 (2006.01)

Patent

CA 2262812

A bioreactor containing living animal cells at density approaching that of normal animal tissue is described. High cell loading is achieved by providing a hydrogel plug which controls fluid flow through the bioreactor during cell loading. Methods for making and using the bioreactor are also described.

L'invention concerne un bioréacteur contenant des cellules animales vivantes, à une densité approchant celle de tissus animaux normaux. On effectue un chargement élevé de cellules au moyen d'un réducteur de débit, qui permet de réguler le débit de liquide dans ledit bioréacteur, au cours dudit chargement des cellules. L'invention concerne également des procédés de fabrication et d'utilisation de ce bioréacteur.

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