Hollow fiber membrane microbiological reactors

C - Chemistry – Metallurgy – 12 – M

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195/145, 195/67

C12M 1/14 (2006.01) C12M 1/00 (2006.01) C12M 1/18 (2006.01)

Patent

CA 1178225

FOLLOW FIBER MEMBRANE MICROBIOLOGICAL REACTORS ABSTRACT OF THE DISCLOSURE Apparatus and methods for microbiological proces- sing of organic materials, particularly for production of valuable products. Asymmetric hollow fibers are employed in a flow reactor, where the hollow fibers have a semipermeable membrane surrounding a lumen, where the semipermeable mem- brane is supported by a sponge structure. The pores of the sponge structure serve as a housing for microorganisms or cells with high density packing of the microorganisms or cells in the pores. Nutrient medium continuously flowing through the lumen provides nutrients to the microorganisms or cells as well as any substrates to be processed by the micro- organisms or cells. The nutrients and substrates diffuse through the semipermeable membrane into the pores, where they are processed, and the metabolic products diffuse into the lumen. The lumen effluent is then processed for the desired products. Optionally, oxygen is provided external to the hollow fiber to enhance the amount of oxygen available to the microorganisms and cells.

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