Hollow glass shell microcarrier for growth of cell cultures,...

Details Hollow glass shell microcarrier for growth of cell cultures,... Hollow glass shell microcarrier for growth of cell cultures,...

C - Chemistry, Metallurgy

12

N

261/2, 195/45, 1

C12N 11/14 (2006.01) C03B 19/10 (2006.01) C03C 11/00 (2006.01) C03C 15/00 (2006.01) C12N 5/00 (2006.01)

Patent

CA 1206900

HOLLOW GLASS SHELL MICROCARRIER FOR GROWTH OF CELL CULTURES, AND METHOD OF SHELL MANUFACTURE Abstract of the Disclosure A hollow silicate glass microsphere for use as a microcarrier in anchorage-dependent cell cultures, and a process for manufacturing such microspheres. The process of manufacture features a method of tailoring the density of the microspheres to the density of the culture medium by first manufacturing the shells over-dense and then immersing the over-dense shells in an etching solution having the density of the culture medium. As the shells become buoyant, they are removed from the solution.

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