G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/53 (2006.01) C12N 15/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/536 (2006.01)
Patent
CA 2287427
Invented is a fluorescence reporter assay system that requires no washing or cell lysis steps, is capable of time resolved fluorescence detection and is suitable for multiplexing. Also invented is a method of conducting high throughput screening using the presently invented fluorescence reporter assay system. Also invented is a method of screening combinatorial libraries using the presently invented fluorescence reporter assay system.
L'invention concerne un système de test par fluorescence de gène reporter qui ne nécessite aucune étape de lavage ou de lyse cellulaire, ce système pouvant effectuer une détection par fluorescence à résolution temporelle et étant approprié au multiplexage. L'invention concerne également un procédé permettant d'effectuer une détection à haut rendement à l'aide d'un système de test de gène reporter par fluorescence. L'invention concerne enfin un procédé de détection de bibliothèques combinatoires utilisé dans le système précité.
Dunnington Damien J.
Moore Keith J.
Gowling Lafleur Henderson Llp
Smithkline Beecham Corporation
Smithkline Beecham P.l.c.
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