Homogenous mammalian hematopoietic stem cell composition

C - Chemistry – Metallurgy – 12 – N

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167/104, 150/13,

C12N 5/06 (2006.01) A61K 35/28 (2006.01) C07K 14/52 (2006.01) C12N 5/08 (2006.01) C12Q 1/02 (2006.01) G01N 33/50 (2006.01)

Patent

CA 1340607

Highly concentrated hematopoietic stem cell compositions are provided which are substantially free of differentiated or dedicated hematopoietic cells. The cells are obtained by subtraction of cells having particular markers and selection of cells having particular markers. The resulting composition may be used to provide for individual or groups of hematopoietic lineages, to reconstitute stem cells of the host, and to identify an assay for a wide variety of hematopoietic growth factors.

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