C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) A61K 39/02 (2006.01) A61P 31/04 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C07K 14/29 (2006.01) C07K 16/12 (2006.01) C12N 1/21 (2006.01) C12N 15/00 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2421952
The present invention is directed to the cloning, sequencing and expression of homologous immunoreactive 28-kDa protein genes, p28-1, -2, -3, -5, -6, -7, -9, from a polymorphic multiple gene family of Ehrlichia canis. Further disclosed is a multigene locus encoding all nine homologous 28-kDa protein genes of Ehrlichia canis. Recombinant Ehrlichia canis 28-kDa proteins react with convalescent phase antiserum from an E.canis-infected dog, and may be useful in the development of vaccines and serodiagnostics that are particularly effective for disease prevention and serodiagnosis.
L'invention concerne le clonage, le séquençage et l'expression de gènes de protéine homologue immunoréactive de 28 kDa, p28-1, -2, -3, -5, -6, -7, -9, provenant d'une famille multigénique polymorphique d'<i>Ehrlichia canis</i>. L'invention concerne également un locus multigénique codant les neuf gènes de la protéine homologue de 28 kDa d'<i>Ehrlichia canis</i>. Les protéines recombinantes de 28 kDa d'<i>Ehrlichia canis</i> réagissent à l'antisérum de la phase de convalescence d'un chien infecté par <i>E.canis</i>, et elles peuvent s'avérer utiles dans le développement de vaccins et de sérodiagnostics, particulièrement efficaces pour la prévention et le sérodiagnostic de maladies.
Mcbride Jere W.
Walker David H.
Yu Xue-Jie
Borden Ladner Gervais Llp
Research Development Foundation
LandOfFree
Homologous 28-kilodalton immunodominant protein genes of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Homologous 28-kilodalton immunodominant protein genes of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Homologous 28-kilodalton immunodominant protein genes of... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2012462