Homologous guluronic acid alginate coating composition for...

A - Human Necessities – 61 – L

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167/327

A61L 27/00 (2006.01)

Patent

CA 2034641

Homoloqous Guluronic Acid Alginate Coating Composition for In-Vivo Application and Implantation and Method of Using Same Abstract Disclosed is a transplantation or implantation composition which provokes a reduced immune response comprising material encapsulated within a physical semi- permeable barrier. At least the outermost layer of the barrier contains alginate comprised substantially of .alpha.- l-guluronic acid with minor amounts .beta.-D-mannuronic acid. The methods of making such a composition and use of the same are also disclosed.

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