Hormone replacement therapy drug formulations for topical...

Details Hormone replacement therapy drug formulations for topical... Hormone replacement therapy drug formulations for topical...

A - Human Necessities

61

K

A61K 31/56 (2006.01) A61K 9/06 (2006.01) A61K 47/10 (2006.01) A61K 47/22 (2006.01)

Patent

CA 2260185

Topical alcoholic or aqueous alcoholic gels containing testosterone, progesterone, estradiol or other hormones have enhanced penetration through skin by including in the formulation 2-n-nonyl-1,3-dioxolane or other hydrocarbyl derivative of 1,3-dioxolane or 1,3-dioxane or acetal, as skin penetration enhancing compound.

Gels topiques alcooliques ou alcooliques aqueux renfermant de la testostérone, de la progestérone, de l'estradiol ou d'autres hormones. Ces gels pénètrent mieux dans la peau grâce à l'ajout à la formulation de 2-n-nonyl-1,3-dioxolane ou d'un autre dérivé hydrocarbylé de 1,3-dioxolane, de 1,3-dioxane ou d'acétal, qui sont utilisés comme composés favorisant la pénétration cutanée.

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