Hormone replacement therapy method and its administration form

Details Hormone replacement therapy method and its administration form Hormone replacement therapy method and its administration form

A - Human Necessities

61

K

A61K 31/57 (2006.01) A61K 31/00 (2006.01) A61K 31/565 (2006.01) A61K 31/567 (2006.01) A61K 45/06 (2006.01) A61P 15/18 (2006.01)

Patent

CA 2433656

Method for hormone replacement therapy, in which at least in the established postmenopause a daily unit with at least one hormonal component, namely with at least estrogen (E) and/or at least one gestagen (G) is administered permanently and continuously every day, characterized in that in at least one ingestion period preceding the permanent administration of hormone daily units is provided an ingestion pause (P), in which either no daily units or placebos or daily units with a much lower estrogen and/or gestagen content than during the permanent administration of hormone daily units in the established postmenopause and during the ingestion phase(s) of the preceding ingestion period are administered, as well as administration form for hormone therapy.

L'invention concerne un procédé destiné au traitement hormonal substitutif, dans lequel au moins durant la post-ménopause établie une dose journalière contenant au moins un composant hormonal, à savoir au moins un oestrogène (E) et/ou au moins un progestatif (G) sont administrés de façon permanente et continue chaque jour. Ce procédé est caractérisé en ce que durant au moins une période d'ingestion précédant l'administration permanente des doses d'hormone journalières, on pratique une pause d'ingestion (P), durant cette pause soit aucune dose journalière ou placebo n'est administré, soit on administre des doses journalières avec une teneur plus faible en oestrogène et/ou en progestatif que lors de l'administration permanente des doses d'hormone journalières durant la post-ménopause établie et durant la/les phase(s) d'ingestion de la période d'ingestion précédente. L'invention concerne également une forme d'administration destinée au traitement hormonal.

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