Hplc avidin monomer affinity resin

B - Operations – Transporting – 01 – J

Patent

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182/2, 252/31, 5

B01J 20/26 (2006.01) B01D 15/08 (2006.01) B01J 20/32 (2006.01) B01J 47/02 (2006.01) C07K 1/22 (2006.01)

Patent

CA 2025487

ABSTRACT Novel, improved ligand-containing media, a method of preparation and use in the production of peptides, proteins, and the like, by chromatographic separation, and more specifically media having permanently attached via a covalent bond to an inert solid substrate an avidin polypeptide ligand in the dissociated renatured form which reversibly binds to certain molecules such as proteins, peptide, nucleotides, oligonucleotides, and the like and to other molecules which bind to avidin via biotinylation or by way of their secondary/tertiary micromolecular structures.

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