G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/567 (2006.01) A61K 31/00 (2006.01) A61K 39/00 (2006.01) A61K 47/30 (2006.01) A61K 47/42 (2006.01) A61K 49/00 (2006.01) A61K 51/00 (2006.01) A61K 51/06 (2006.01) A61K 51/08 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2512513
Disclosed are methods for detecting neoplastic or damaged cells and for detecting multidrug resistance in neoplastic or damaged cells by detecting an increase in the cell surface expression of a heat shock cognate (HSC70) protein 70 on the surface of such a multidrug resistant neoplastic or damaged cells as compared to the level of expression of the HSC70 protein on the surface of a normal cell.
La présente invention se rapporte à des procédés de détection de cellules néoplasiques ou endommagées et de détection d'une résistance à de multiples médicaments dans des cellules néoplasiques ou endommagées au moyen de la détection d'un accroissement dans l'expression superficielle cellulaire d'une protéine 70 apparentée de choc thermique (HSC70) à la surface de telles cellules néoplasiques ou endommagées résistant à de multiples médicaments par comparaison au niveau d'expression de la protéine HSC70 à la surface d'une cellule normale.
Bonneau Anne-Marie
Dallaire Frederic
Georges Elias
Serfass Lucile
Aurelium Biopharma Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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