Hsp and supraventricular arrhythmia

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/02 (2006.01) A61K 48/00 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2590061

The invention relates to the field of biology, molecular biology and medicine More specifically, the invention relates to a method for at least in part preventing or delaying or decreasing damage to a cardiac cell induced by a supraventricular arrhythmia. The invention provides a method for preventing, delaying or decreasing damage to a cardiac cell induced by a supraventricular arrhythmia comprising increasing the amount of at least one heat shock protein (HSP) or a functional equivalent and/or a functional fragment thereof , e. g. HSP27 or its functional equivalent HSP25, in said cardiac cell.

La présente invention relève du domaine de la biologie, de la biologie moléculaire et de la médecine. Cette invention se rapporte plus spécifiquement à un procédé visant à prévenir, à retarder ou à réduire au moins en partie la détérioration d'une cellule cardiaque induite par une arythmie supraventriculaire. Selon cette invention, le procédé visant à prévenir, à retarder ou à réduire la détérioration d'une cellule cardiaque induite par une arythmie supraventriculaire consiste à augmenter la quantité d'au moins une protéine de choc thermique (HSP) ou d'un équivalent fonctionnel et/ou d'un fragment fonctionnel de celle-ci dans la cellule cardiaque.

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