Htlv-i and htlv-ii gp21 derived peptides for use in diagnostics

Details Htlv-i and htlv-ii gp21 derived peptides for use in diagnostics Htlv-i and htlv-ii gp21 derived peptides for use in diagnostics

C - Chemistry, Metallurgy

07

K

C07K 14/155 (2006.01) C07K 7/06 (2006.01) C07K 14/15 (2006.01) C07K 16/10 (2006.01) G01N 33/569 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2155001

Novel HTLV-I and HTLV-II peptides are disclosed for use in diagnostic assays for detecting and confirming HTLV-I and HTLV-II infection in human sera. The peptides are derived from analogous regions of HTLV-I and HTLV-II gp21 envelope protein, and are diagnostic of HTLV-I or HTLV-II infection. The invention also includes an assay kit and method for detecting, and discriminating between, HTLV-I and HTLV-II infection in humans.

L'invention concerne de nouveaux peptides, utilisés dans des méthodes diagnostiques pour la détection et la confirmation de l'infection à HTLV-1 et HTLV-II dans le sérum humain. Lesdits peptides sont dérivés de régions analogues de la protéine d'enveloppe gp21 de HTLV-I et HTLV-II et constituent des moyens de diagnostic de l'infection à HTLV-I et HTLV-II. L'invention porte également sur un matériel et une méthode de détection et de différenciation de l'infection à HTLV-I et à HTLV-II chez l'homme.

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