Htm4, methods of treatment and assays, agonists and antagonists

Details Htm4, methods of treatment and assays, agonists and antagonists Htm4, methods of treatment and assays, agonists and antagonists

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/45 (2006.01) A61K 38/46 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2264490

The invention relates to a recombinant DNA molecule which encodes a HTm4 protein, a transformed host cell which has been stably transfected with a DNA molecule which encodes a HTm4 protein and a recombinant HTm4 protein. The invention also relates to a method for detecting the presence of a hereditary atopy, to agonists and antagonists of a HTm4 protein, and to their diagnostic and therapeutic use.

L'invention a trait à une molécule d'ADN recombinée codant pour une protéine HT¿m4?, une cellule hôte transformée qui a été transfectée de façon stable avec une molécule d'ADN codant pour une protéine HT¿m4?, et une protéine HT¿m4? recombinée. Cette invention a également trait à un procédé permettant de détecter la présence d'une atopie héréditaire, à des agonistes et à des antagonistes d'une protéine HT¿m4?, à leur diagnostic et à leur usage thérapeutique.

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