Hu antigen-derived peptides and uses thereof

Details Hu antigen-derived peptides and uses thereof Hu antigen-derived peptides and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 38/16 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 14/00 (2006.01) C07K 14/47 (2006.01) C07K 14/52 (2006.01) C07K 16/00 (2006.01) C12N 5/00 (2006.01) C12N 15/63 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2387391

The present invention relates to Hu antigen-derived peptides and to their use, and more particularly to their use in the diagnostic, in the prevention and in the treatment of certain types of cancer and neuronal damage. The immunogenic peptides of the invention are capable of generating cytotoxic CD8 T- lymphocytes (CTLs) which may eliminate undesirable cells such as SCLC cancerous cell, without reacting against non-cancerous such as neural cells. The invention also provides nucleotides coding these immunogenic peptides and antibodies binding thereto.

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