Human abo blood group-binding lactobacilli

Details Human abo blood group-binding lactobacilli Human abo blood group-binding lactobacilli

C - Chemistry, Metallurgy

12

N

C12N 1/20 (2006.01) A23C 9/127 (2006.01) A23L 1/30 (2006.01) A23L 2/38 (2006.01) A23L 2/52 (2006.01) C12Q 1/02 (2006.01) G01N 21/27 (2006.01) G01N 33/543 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2588940

Lactic acid bacteria are screened by the surface plasmon resonance spectroscopy with the use of human intestinal mucin and blood type antigens as probes. To adapt to the mass-scaled screening, it is attempted to set selection standards for the screening of lactic acid bacteria as described above. As a result, it is found out that lactic acid bacteria respectively matching ABO blood types can be screened by using 100RU under definite conditions as the standard of binding of bacteria. 238 strains of lactic acid bacteria are subjected to this screening. Further, a test for examining the suitability for yogurt production is performed. Finally, strains matching individual blood types of A, B and O are clarified in practice.

Les bactéries de l'acide lactique sont criblées par spectroscopie par résonance plasmonique de surface, la mucine intestinale humaine et des antigènes des types sanguins étant utilisés en tant que sondes. Afin de s'adapter à un criblage de grande échelle, on s'efforce de définir des normes de sélection pour le criblage des bactéries de l'acide lactique tel que décrit ci-dessus. Il s'avère par conséquent que les bactéries de l'acide lactique correspondant respectivement aux types sanguins ABO peuvent être criblées au moyen de 100RU à des conditions spécifiques en tant que norme de liaison des bactéries. 238 souches de bactéries de l'acide lactique sont soumises à ce criblage. Ensuite, un test destiné à déterminer l'aptitude à la production de yaourt est réalisé. Enfin, les souches correspondant aux types sanguins individuels A, B et O sont clarifiées en pratique.

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