Human abo blood group-binding lactobacilli

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 1/20 (2006.01) A23C 9/127 (2006.01) A23L 1/30 (2006.01) A23L 2/38 (2006.01) A23L 2/52 (2006.01) C12Q 1/02 (2006.01) G01N 21/27 (2006.01) G01N 33/543 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2588991

Lactic acid bacteria are screened by the surface plasmon resonance spectroscopy with the use of human intestinal tract mucin and blood type antigens as probes. To fit to the large-scaled screening, attempts are made to specify selection standards in the screening of lactic acid bacteria. Thus, it is found out that lactic acid bacteria fitting to ABO blood types can be screened by using 100RU as a standard for judging the binding of the bacteria under certain conditions. 238 strains of lactic acid bacteria are subjected to this screening. Further, a test for judging the suitability for yogurt production is performed. As a result, strains fitting to the blood types A and O are found out in practice.

On crible des bactéries lactiques par spectroscopie de résonance plasmon de surface en utilisant la mucine du tube intestinal humain et des antigènes de groupes sanguins comme sondes. Pour s'adapter au criblage à grande échelle, on essaie de spécifier des standards de sélection lors du criblage de bactéries lactiques. Ainsi, on trouve qu'on peut cribler des bactéries lactiques correspondant aux groupes sanguins ABO en utilisant 100RU comme standard pour évaluer la formation de liaisons avec les bactéries dans certaines conditions. On soumet 238 souches de bactéries lactiques à ce criblage. En outre, on effectue un test servant à évaluer leur caractère approprié pour la production de yoghourt. En conséquence, on trouve dans la pratique des souches correspondant aux groupes sanguins A et O.

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