Human akt-3

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/54 (2006.01) A61K 38/45 (2006.01) A61K 39/395 (2006.01) C07K 16/40 (2006.01) C12N 5/10 (2006.01) C12N 9/12 (2006.01) C12N 15/10 (2006.01) C12N 15/70 (2006.01) C12N 15/85 (2006.01) C12Q 1/48 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2355834

There is disclosed a nucleic acid molecule encoding human Akt-3 protein or a functional equivalent or bioprecursor thereof comprising the amino acid sequence illustrated in Sequence ID No. 3. The human Akt-3 protein itself also forms part of the invention. The nucleic acid molecule and the human Akt-3 protein may themselves be used as medicaments, or in the preparation of medicaments for treating cancer, in their own right or in the form of a pharmaceutically acceptable carrier, diluent or excipient thereof. Further disclosed are methods of identifying agents which influence the activity of a human Akt-3 protein.

La présente invention à trait à une molécule d'acide nucléique codant la protéine humaine Akt-3 ou un équivalent fonctionnel ou un de ses bioprécurseurs comprenant la séquence d'acide aminé illustrée dans la séquence ID No. 3. La protéine humaine Akt-3 elle-même représente également une partie de l'invention. On peut utiliser la molécule d'acide nucléique et la protéine humaine Akt-3 elles-mêmes comme médicaments, ou dans la préparation de médicaments permettant de traiter le cancer, sous leur forme directe ou sous la forme d'un véhicule pharmaceutiquement acceptable, d'un diluant ou d'un excipient de celles-ci. L'invention porte aussi sur des techniques permettant d'identifier des agents qui influent sur l'activité de la protéine humaine Akt-3.

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