Human .alpha.-1-antitrypsin derivatives, and a production...

C - Chemistry – Metallurgy – 12 – N

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530/13, 167/103.

C12N 15/15 (2006.01) C07K 14/81 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 15/10 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1341216

L'invention concerne un analogue de l'.alpha. 1 -anti- trypsine humaine caracterisé en ce qu'il s'agit de tout ou partie de la protéine correspondant a l'.alpha. 1 -antitrypsine humaine dans laquelle, en position 358, l'amino-acide est choisi parmi l'arginine et les amino-acides naturels peu ou pas oxydables lorsqu'ils sont integrés dans une protéine.

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