Human and murine cytokine polypeptides

Details Human and murine cytokine polypeptides Human and murine cytokine polypeptides

C - Chemistry, Metallurgy

12

N

C12N 15/19 (2006.01) C07K 14/52 (2006.01) C07K 16/24 (2006.01) C12P 21/02 (2006.01) G01N 33/53 (2006.01) G06F 19/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2462644

This invention relates to IMX7189 cytokines and to new members of the human cytokine polypeptide family, methods of making such polypeptides, and to methods of using them to treat conditions and diseases involving proliferation and/or differentiation of cells from pluripotent stem cell precursors, and to identify compounds that alter cytokine polypeptide activities.

L'invention concerne les cytokines IMX7189 ainsi que des nouveaux membres de la famille des polypeptides de cytokine humaine, des procédés d'obtention de ces polypeptides, et des procédés d'utilisation de ces polypeptides pour traiter des états pathologiques et des maladies impliquant la prolifération et/ou la différenciation de cellules à partir de précurseurs de cellules souches pluripotents, et pour identifier des composés qui altèrent les activités des polypeptides de cytokine.

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