Human anti-idiotypic antibody fragments that mimic her-2/neu

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/42 (2006.01) C12N 5/0784 (2010.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2549937

This invention relates to human anti-idiotypic antibody fragments, especially scFv, characterized by the ability to mimic Her-2/neu tumor associated antigen. These antibody fragments are promising candidates for active immunotherapy for cancer patients positive for Her-2/neu.

La présente invention concerne des fragments d'anticorps anti-idiotypique humain, notamment scFv, caractérisés par leur aptitude à imiter l'antigène spécifique de tumeurs Her-2/neu. Ces fragments d'anticorps sont des candidats prometteurs pour une immunothérapie active anti-Her-2/neu destinée à des cancéreux.

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