Human anti-ifn-y neutralizing antibodies as selective ifn-y...

Details Human anti-ifn-y neutralizing antibodies as selective ifn-y... Human anti-ifn-y neutralizing antibodies as selective ifn-y...

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 39/395 (2006.01) C07K 16/24 (2006.01)

Patent

CA 2501653

This invention provides antibodies that interact with or bind to human interferon-gamma (IFN-.gamma.) and methods for treating IFN-.gamma. mediated diseases by administering a pharmaceutically effective amount of antibodies to IFN-.gamma.. Methods of detecting the amount of IFN-.gamma. in a sample using antibodies to IFN-.gamma. are also provided.

Cette invention porte sur des anticorps qui ont une interaction ou se lient à l'interféron-gamma (IFN-.gamma.) humain et sur des procédés de traitement de maladies induites par IFN-.gamma. qui consistent à administrer une quantité efficace d'un point de vue pharmaceutique d'anticorps contre IFN-.gamma.. L'invention porte également sur des procédés de détection de la quantité d'IFN-.gamma. dans un échantillon au moyen d'anticorps contre IFN-.gamma..

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